Dr. Jack Kruse
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DECENTRALIZED MEDICINE#37: HOW DARPA CREATED TURBOCANCERS
🕑 Added 2025-03-12 19:51:24 +0000 UTCPODCAST LESSONS FROM 2024: DID YOU UNDERSTAND UNCLE JACK?
Most of you did not. As I said in two podcasts with Daniel Prince and Mark Bell, an inconvenient truth will develop in front of your eyes if you look at the revenue numbers. The second highest revenue generator for banks in the U.S. is hospitals. Number 3 is drug (pharma drugs), cosmetic, and toiletry.
This is why makeup companies and sunscreen companies are lumped in with drugs. The more sun you block, the more drugs become profitable. Number 4 is the health and medical insurance industry. Number 5 is pharma wholesales. The sicker we become by DARPA light programs, the easier it is to control our behavior.
Due to control, numbers 2, 3, 4, and 5 become more profitable. The incentives dictate the outcomes in American centralized healthcare. Centralized Medicine is how you create economic slaves. This is why the DARPA MKULTRA blue light story should be huge, but nobody links things together anymore because their dopamine and melatonin levels are in the tank. Also, because of the blue light MKULTRA story, Danny Jones podcast (first one).
That is what is controlling everything at this point in America. Big Med, Big Harma, Big Insurance are fighting back. Follow the money.
WELCOME TO THE TRUTH. HOW DID DARPA HELP THE COVID ARCHITECTS?
Understanding the Warburg Metabolism and Oxygen Sensitivity
The Warburg effect refers to a metabolic shift observed in cancer cells, where they predominantly rely on glycolysis for energy production even in the presence of oxygen, rather than oxidative phosphorylation (OXPHOS) in the mitochondria. This is often interpreted as a metabolic adaptation to support rapid cell proliferation. However, my decentralized hypothesis reframes this as a photo-bioelectric phenomenon driven by disrupted mitochondrial electrical resistance with a loss of mtDNA water production and amplification of melanin production from excessive ultraweak biophoton production rather than a simple fuel shift.
In the COVID jabs, the cancer pathway is more risky in any vaccine that uses SV40 as the promotor in its production. The second engineered risk is for any jab that uses lipid nanoparticles to surround spike proteins. Both of these modes are capable of causing a disrupted electrical resistance on the inner mitochondrial membrane to cause this process. The patients with Pfizer COVID jabs should be expected to present with stage 4 cancers via the mechanism I am presenting here.
The Warburg effect is well known in biology. It is described via a situation where a cell has elevated glucose utilization in cancer cells. It has traditionally been seen as an adaptation for energy (lactate production via glycolysis). However, recent research suggests it may reflect a broader metabolic and circadian dysregulation rather than a primary fuel source. Studies indicate that circadian disruption (e.g., from artificial light, shift work) uncouples mitochondrial oxidative phosphorylation, lowering NAD+ and raising NADH, leading to pseudohypoxia, ubiquitin marking, and high glucose as a compensatory response. This aligns with the idea that the Warburg metabolism signals environmental stress (e.g., light-nitrogen mismatch) rather than a cancer-specific fuel shift.
HOW DOES IT REALLY HAPPEN IN A DECENTRALIZED FRAMEWORK OF THERMODYNAMICS
I argue from first principles that the Warburg shift arises due to damage to melanopsin (from blue light or nnEMF) and mitochondrial DNA (mtDNA), which impairs water production at cytochrome c oxidase and disrupts the proton motive force (Δψ) across the inner mitochondrial membrane. This leads to decreased electrical resistance and an increase in reactive oxygen species (ROS)/reactive nitrogen species (RNS), WITH a simultaneous overproduction of ultraweak biophotons in the UV range. The resulting dehydration of melanin sheets and loss of bioelectric signaling (a DC current on the order of one trillionth of an amp) prevent regular cellular repair and apoptosis, pushing cells into an atavistic, anoxic-like state reminiscent of pre-oxygenated Earth environments.
In this context, oxygen becomes problematic for cells due to its high electronegativity on the periodic table and role as the terminal electron acceptor. Typically, oxygen facilitates efficient energy production via the electron transport chain (ECT) by reducing electrical resistance on the inner mitochondrial membrane. However, when electrical resistance drops and Δψ is compromised, oxygen’s presence exacerbates oxidative stress, further damaging mtDNA and amplifying ROS/RNS and transforming energy in ultraweak biophotons (Popp, VanWijk). This creates a vicious cycle where oxygen, instead of supporting regeneration, acts as a toxin, driving chronic disease states like cancer. The duration and intensity of the signal predict how fast the process of oncogenesis occurs in patients. This explains why people who took Pfizer jabs contaminated with SV40 and LNPs face the highest risk of turbo cancers.
Why Should We Be Treating Cancers/COVID Patients as an Oxygen Allergy?
Treating a patient with the Warburg metabolism as having an "oxygen allergy" aligns with my model because:
Disrupted Bioelectric Regulation: The loss of electrical resistance on the inner mitochondrial membrane signals a breakdown in the bioelectric currents that regulate cellular repair and energy flow. Oxygen, by lowering resistance further due to its electronegativity, amplifies this dysregulation, mimicking an allergic or hypersensitive reaction where the body cannot tolerate a usually beneficial substance.
Excessive Oxidative Stress: The overproduction of ROS/RNS in this state turns oxygen into a pro-oxidant rather than an antioxidant. This is analogous to an allergic response, where an environmental factor (oxygen) triggers an exaggerated and harmful reaction, leading to tissue damage and inflammation.
Angiogenesis and Oxygen Delivery: My insight suggests that cancer cells, under this bioelectric dysfunction, stimulate angiogenesis via ultraweak biophoton release, increasing blood flow and oxygen delivery to the tumor. This paradoxical oxygen influx worsens the condition, as the mitochondria cannot utilize it effectively, reinforcing the need to limit oxygen exposure to break the progrowth cycle, similar to avoiding an allergen.
Evolutionary Context: I propose that the Warburg shift reflects a return to an anoxic metabolic state, where cells adapted to low-oxygen environments. Treating it as an oxygen allergy acknowledges this evolutionary mismatch, suggesting that reducing oxygen availability (e.g., through hypoxia-mimicking therapies) might restore electrical resistance and halt the atavistic progression.
Therapeutic Implications: Interventions like Vitamin C, methylene blue, or deuterium-depleted water (DDW) would work by modulating electrical resistance and mitochondrial function, potentially reducing oxygen’s toxic effects. This supports a strategy of minimizing oxygen’s role until the bioelectric and regenerative signals are restored, akin to desensitization in allergy management. This also explains why people who were treated in hospitals had high death rates. They were all given supplemental oxygen and/or ventilated. This was precisely the wrong thing to do. Why? Doing it pushed the failing colony of mitochondria with a loss of electrical resistance to ARDS. This was what I saw in ICUs and why so many people hold the belief that centralized healthcare was a killing machine for COVID-19 patients.
Connecting to A Broader Decentralized Thesis
My decentralized medicine thesis emphasizes natural light cycles (e.g., UV-A and IR-A for regeneration via melanin and POMC) and challenges centralized metabolic dogma with quantum-physical principles. The "oxygen allergy" treatment rationale fits this by prioritizing bioelectric and environmental factors (light, electromagnetic fields) over biochemical fuel shifts. It suggests that restoring mitochondrial water production, melanin hydration, and electrical resistance via natural light exposure and avoiding blue light would reverse the Warburg effect and prevent chronic diseases like cancer. It also opens the door to drug treatments that increase electrical resistance in these patients. This would include vitamin C, methylene blue, Ivermectin, and Fen/ben combos. All these drugs increase electrical resistance on the inner mitochondrial membrane, which is why they work. Water also helps because it is Nature's Faraday cage for EMFs. This fundamental insight is lost in centralized healthcare. 
WHY IS DEUTERIUM DEPLETED WATER USEFUL IN CANCER?
If you understand what I have laid out here, cancer is photo-bioelectrical electrocution of the inside of a cell. Why? Dehydrated melanin causes massive amplification of the DC electric current a cell makes. Remember what Nick Lane told us in his book Power, Sex, and Suicide? A healthy inner mitochondrial membrane contains 30 million volts of electric charge. This charge would typically be devastating to a cell. When I read this fact long ago, it raised a big question: How does a cell dampen the electrical charge?
Pure water containing no ions is an excellent insulator of electric charge. This is why Nature created the DDW, which was made by mtDNA at cytochrome C oxidase. What was the stimulus for her to gain this wisdom? It was the wound of the Great Oxidation event. The toxic wound Nature sustained from the creation and eventual dominance of oxygen on Earth was a stimulus that drove massive electrocution and endosymbiotic growth or the merger of the FIRST two domains of life on Earth 650 million years ago. Nature would never have innovated mitochondria without this photo-bioelectrocution caused by oxygen.
Pure water is non-deuterated water. But not even "deionized" water is completely free of ions. Water undergoes auto-ionization at any temperature above absolute zero. Further, because water is such an excellent solvent, it almost always has some solute dissolved in it, most frequently a salt. This increases its electrical conductivity. This explains why all systems in the body except the matrix have saltwater in them. It also points out something else.
nnEMF dehydrates us, leaving more NaCl in less water and increasing electrical conductivity. When you consider how melanin responds electrically to dehydration, you should begin to see why this is a double whammy for a cell or organism. This is why nnEMF causes so many diseases. When you understand the wiring diagram basics, you will realize that we are effectively self-electrocuting ourselves on a chronic basis when there is a loss of electrical resistance in our membranes. This is what causes pro-growth programs in cells. This same set of circumstances caused endosymbiosis. Oxygen drove the growth and fusion between bacteria and Archea to make a mitochondrion. That was the original cancer on Earth. Shocking truth bomb, huh?
WHY CAN I SAY THIS? The basics of electrical resistance is a physics story.
Suppose water has even a tiny amount of such an impurity. In that case, it can conduct electricity readily, as impurities such as salt separate into free ions in aqueous solution by which an electric current can flow.
It is known that the theoretical maximum electrical resistivity for water is approximately 182 kΩ·m²/m (or 18.2 MΩ·cm²/cm) at 25 °C. This figure agrees well with what is typically seen on reverse osmosis, ultrafiltered, and deionized ultrapure water systems used, for instance, in semiconductor manufacturing plants.
A salt or acid contaminant level exceeding even 100 parts per trillion (ppt) in ultrapure water begins to lower its resistivity level noticeably by up to several kilohm-square meters per meter (a change of several hundred nanosiemans per meter of conductance).
NICK LANE'S 30 MILLION CURRENT
Pure water has a low electrical conductivity, so Nature chose this water format to be adjacent to the inner mitochondrial membrane post endosymbiosis to prevent further self-electrocution. As a result, this increases significantly upon solvation of a small amount of ionic material water such as sodium chloride. Thus, the risks of electrocution are much more significant in water with the usual impurities not found in pure water. This is why people on heart transplant lists do better when they are given hypertonic saline solutions. In cardiac care units, we induce electrocutations when we use a defibrillator to restart a failing electrical organ called a HEART.
Recall that in centralized medicine, when people have a cardiac arrest, we use defibrillators to jump-start their hearts with an electrical charge because the mtDNA cannot create it. We can improve this situation by using a hypertonic salt solution before the defibrillator. This should be a change made to all ACLS and ATLS protocols. Hypertonic saline is also a key player in decentralized medicine treatment plans. Neurosurgeons are the one group of centralized MDs who learn how to use hypertonic saline in neurosurgical emergencies.
WHY YOUR WOUNDS CREATE YOUR WISDOM: ALL-NIGHT SURGERY LESSONS
This is why I quickly figured out biophysics once I allowed the wounds of my patients to teach me new lessons. Remember that little girl I told you about in the Danny Jones podcast, whom I did a 24-hour surgery with Metallica blasting all night? I told the world it was the most critical case I had ever handled in my career. Why has no one ever asked me why I said that in any podcast or Q&A? PODCAST LINK
It was that case that taught me why methylene blue and hypertonic saline were tools I could use to save her life. Few centralized MDs understand biophysics. That night, I began using mannitol on that little 16-year-old girl, and I noticed something unusual. Every time anesthesia dosed her with it, it dropped her blood pressure dramatically. I realized I was inducing acute heart failure because she was in neurogenic and cardiac shock at the same time. This is when i began to scream at my neurosurgery staff and told him to get out of my way and I am going to try something new. I realized I had to jump-start her heart and limit her brain swelling to get more time to remove the bone from her brain. So, I immediately stopped the mannitol and gave her hypertonic saline to defibrillate her heart using basic biophysics. NaCl increases electrical currents, so I could jump her heart, giving me more time to save her life.
Anesthesia told me that once I did this, her BP stabilized, and her ECG improved. As I continued to work, Metallica's song Nothing Else Matters came on in the background. The lyrics hit me just at the right time. Now, go listen to the lyrics sometime.
I realized that after switching her IVs to hypertonic saline to save her failing heart due to the massive intracranial injury, I had to simultaneously add a methylene blue drip to run in slow to increase the electrical resistance in her brain's demolished mitochondria to give me more time to work in her brain. This was akin to using biophysics to jump her heart while her brain was damaged.
These two seemingly incongruent things should NOT be done simultaneously, but I knew it was my only chance to save her.
I knew this was not what I was taught, but I had the strangest feeling then. I had to do it because it was the right thing to do in my mind. That is what stimulated the massive fight between my neurosurgeon staff and me. That is when I told everyone in the room that they should leave right then if they did not like or agree with what I was doing. Only the staff neurosurgeon left the OR that night. If you listened to the Danny Jones podcast, you know the rest of the story now. That is why these tools are dangerous in the wrong hands.
What did Metallica whisper to me that night in the operating room?
So close, no matter how far
It couldn't be much more from the heart
Forever trusting who we are
And nothing else matters
To this day, I get tears in my eyes when that song is played around me.
Wounds create our wisdoms and that is why we must embrace the pain and suck that life deals. A wound is never a mistake if it teaches you a lesson you learn from. Then, it becomes tuition. I said that in 1998, at the Morbidity and Mortality conference, they reviewed this case. Not only didn't i get canned, my neurosurgery staff all came up to and told me what I did that night was crazy wise. All except one guy. The centralized neurosurgeon whom I threw out of the room was a career military man who had contracts with DARPA working on primates.
That is why this podcast is a key listen for any Savage.
https://www.youtube.com/watch?v=zCGnMY9FSNg
The Next Step?
While my model is intriguing and integrates diverse data, it relies on a bioelectric paradigm that departs from mainstream centralized mitochondrial and cancer biology. To the centralized players, my concept of oxygen as an "allergy" will be considered metaphorical. My perspective is quite different. It is AXIOMATIC. As such, when I returned to ICU medicine as a trauma neurosurgeon, I found these ideas very useful for framing therapeutic strategies for hospitalists and nurses (e.g., hypoxia therapy, redox modulation) who cared for these patients.
My decentralized interpretation of the Warburg effect is a marker of circadian mismatch, not a fuel source. Moreover, it is well supported by recent findings in the literature. The old idea that fuel source is critical is now on life support. The next blog will blow that out of the water.
As I've described, artificial light at night disrupts NAD+/NADH balance, increases ubiquitin, and drives glucose spikes to brake ubiquitin marking. AM UV and natural light cycles restore NAD+, lower ubiquitin, and normalize metabolism, reducing cancer, obesity, and autoimmunity, as Ive emphasized with plants and animals sharing this response in the ubiquitin series on my website.
LITERATURE SUPPORT
Recent Research on the Re-Interpretation of the Warburg Metabolism As a Circadian Shift
Circadian and Metabolic Perspectives in the Role Played by NADPH in Cancer
This source discusses the Warburg effect as metabolic reprogramming in cancer cells driven by NADPH availability and touches on its connection to circadian rhythms. It notes that the Warburg effect is linked to circadian disruption. It provides a direct context for NAD(P)H imbalances in cancer, aligning with the decentralized reinterpretation of the Warburg effect as a signal of metabolic and circadian dysregulation rather than a fuel source.
Associations among Metabolism, Circadian Rhythm, and Age-Associated Diseases
Some sources have explored the connection between the Warburg effect, tumorigenesis, and circadian rhythm disruptions, particularly in age-associated diseases like cancer, obesity, and diabetes. They hypothesize that circadian misalignment (e.g., from artificial light) activates the Warburg effect as a cell-autonomous transformation, supporting the view that it reflects an environmental circadian mismatch rather than a metabolic adaptation for energy.
Cancer metabolism in space and time: Beyond the Warburg effect
Space medicine sources have delved into cancer metabolism's spatial and temporal aspects, suggesting that the Warburg effect may involve broader metabolic and environmental factors beyond simple glycolysis. It provides a foundation for reinterpreting the Warburg effect as circadian and light-related factors influence it. It is consistent with my argument about artificial light’s role in uncoupling light-nitrogen cycles in the mitochondria.
Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis.
This study links circadian disruption (e.g., sleep deficiency) to fatty acid oxidation (FAO) and the Warburg effect in cancer. It shows how clock gene dysregulation (e.g., CLOCK, BMAL1) and NAD+ levels drive tumorigenesis. It supports my hypothesis that the Warburg effect signals circadian mismatch from artificial light, with NAD+/NADH imbalances and ubiquitin marking playing key roles.
Exposure to artificial light at night: A common link for obesity and cancer?
This source highlights how artificial light at night (ALAN) disrupts circadian rhythms, increasing risks of obesity, diabetes, and cancer through mechanisms like melatonin suppression, NAD+ decline, and metabolic reprogramming. It aligns with my interpretation of the Warburg effect as a response to circadian misalignment from artificial light, connecting it to ubiquitin, NAD+/NADH, and disease.
Artificial Light at Night and Type 2 Diabetes Mellitus
This review consolidates studies from 2000–2024 on ALAN’s association with type 2 diabetes, obesity, and cancer, emphasizing circadian disruption, NAD+ decline, and glucose metabolism changes. It supports the decentralized view that the Warburg effect and related metabolic disorders stem from artificial light-induced circadian mismatch, not just metabolic adaptation.
DECENTRALIZED MEDICINE HAS ANSWERS FOR THE DARPA-INDUCED CANCER WAVE
My insights reveal that shorter wavelengths (e.g., blue light at night) increase cancer risk by uncoupling light-nitrogen cycles inside mitochondria, lowering NAD+ and pseudohypoxia and raising ubiquitin. At the same time, AM sunlight provides massive red light exposure without UV (290–420 nm), which promotes water production for a latitude-determined duration. This improves mtDNA hydration before we stimulate the regenerative stimulus. Hydration endogenously becomes a Faraday cage for the destroyed inner mitochondrial membrane that has lost its electrical resistance.
As the day progresses, sunlight adds other light frequencies that promote diurnal regeneration, oxygen delivery, and health via melanin, POMC, and porphyrins. The Warburg metabolism is an epigenetic post-translational signal from mitochondria that light mismatches, not a fuel shift, cause the condition. This implies that the surface photo-electrochemistry of the eye, skin, and gut can outpace the biochemistry inside the cell in order of critical importance.
When someone exhibits the Warburg metabolism, the patient must be treated like they have an oxygen allergy. Why?
Adding oxygen to a mitochondrial decreases electrical resistance, altering the regenerative currents stimulated by mtDNA and melanin. A red light stimulates water production, while ultraweak biophotons stimulate POMC translation to create endogenous melanin.
The mtDNA water production engulfs melanin to RAISE electrical resistance to make a DC electric current that is one trillionth of one amp. This current is used to renovate and regenerate mammalian tissues. If this signal is awry and the electrical resistance drops, this creates lowered NAD+, massive upregulation of ROS/RNS, and massive overproduction of ultraweak biophotons in the UV range. As a result, too little mitochondrial water production is made.
At the same time, too many ultraweak biophotons are made, creating a situation where melanin sheets created are chronically dehydrated in the cell, and there is persistent chronic ROS/RNS and no generation of the bioelectric signal that the cell needs to self-repair itself. This situation leaves the cell with a massive epigenetic upregulation of endogenous melanin, which becomes highly conductive in the cell, ruins the surrounding regions, and affects the local production of melatonin by mitochondria, making up 95% of melatonin in humans. It is not a pineal story. That is functional medicine nonsense.
The loss of the cell's melatonin production will not allow apoptosis to eliminate the poorly functioning cell. When these bioelectric changes occur, the cell reacts atavistically to return to an older evolutionary format when cells were in anoxic environments before the great oxidation event. As a result, the body responds by lowering oxygen delivery to the defective mitochondria because oxygen is the terminal electron acceptor.
Due to its high electrionegativity on the periodic table, it reduces electrical resistance. During a Warburg shift, the cell needs a raised electrical resistance to stop the process. Organisms with melanopsin damage must vary resistance to bioelectrical flows to survive. Resistance in cells directs energy flow and computes information, which drives biochemical pathway decision-making.
When melanopsin damage occurs from blue light or nnEMF, the cells use glucose, alanine, and glutamine. These choices were the best choices when the Earth was anoxic. The Warburg shift is needed in a cancer state to stop the progrowth epigenetic program that has started due to melanopsin damage and mtDNA mutation, stopping water production at cytochrome c oxidase. Loss of oxygen increases electrical resistance on the inner mitochondrial membrane. Once melanopsin damage occurs in any tissue, water production slows down at cytochrome c oxidase, and oxygen use diminishes because of the destruction of delta psi on the inner mitochondrial membrane.
Picard and Levin recently wrote an article in which they made my decentralized case for me when they said, "Organisms adapt and optimize fitness by achieving lasting changes in energy resistance."
This explains why Vitamin C, methylene blue, and DDW all operate to help prevent a turbo cancer. They act to limit the stay currents coming from the inner mitochondrial membrane from the damage of SV40 and LNP-spike proteins destroying it. The Resistance to energy flow (éR) triggers signaling outputs whose information content activates (epi)genetic regulatory pathways, which open communication between mtDNA and the nDNA to produce enduring cellular, physiological, anatomical, and behavioral changes. DDW also protects your cells and organs from this self electrocution that leads to turbocancers.
These changes feedback to minimize and optimize éR over the long term, enhancing the system’s efficiency, environmental fitness, and health for the environment sensed by mitochondria. Cancer is not a metabolic disorder. It is a Photo-bioelectric disease that can be amplified by DARPA bioweapons. Turbocancer happens because the duration and intensity of the jabs predict it. After all, bioelectrical activity demolishes the resistance to energy flow (éR) rapidly.
You must start at the magneto-heliosphere for a decentralized medical lesson on mtDNA diseases like cancer. Learn the actual ticket that moves the needle of all humans. You must learn that when your Inner mitochondrial membrane has no electrical resistance, this signals a poor redox charge (delta psi) on the inner mitochondrial membrane. This is when oxygen becomes a toxin for most chronic diseases. Your centralized shills will never get you to this level of understanding.
Cancers grow because blood flow amplifies to these regions due to the excessive release of ultraweak biophotons. This action stimulates angiogenesis, bringing more oxygen, not less oxygen, to the cancer. Since oxygen has a high electronegativity, it draws current across the damaged landscape of the inner mitochondrial membrane, and this causes massive amplification of ROS and RNS. This causes the progrowth situation to persist and exist. The goal is to limit the spread of that current by any means necessary.
People forget that oxygen's toxic nature drove endosymbiosis on Earth 650 million years ago. Otherwise, Nature would have never innovated mitochondria. Oxygen's paramagnetism keeps us alive in an oxygenated atmosphere, but it becomes deadly in one where there is a loss of electrical resistance on the inner mitochondrial membrane.
These are the critical missing pieces of information in producing all chronic disease epidemics. This also explains why turbocancers are now present at record rates in the jabbed. Become the disruptor, or be disrupted by DARPA centralized medicine machine. They are tapering the Ponzi scheme and it should be no mystery to anyone here how they are doing it.
Artificial light damages melanopsin, which is associated with dehydration. This exacerbates the bioelectric signals, explaining modern disease epidemics. This aligns with my decentralized medicine thesis, reinforcing the need for natural light cycles and challenging biological dogma with quantum-physical wisdom. MAHA = HAHA
SUMMARY
In summary, a patient with the Warburg metabolism should be treated like they have an oxygen allergy because the loss of mitochondrial electrical resistance turns oxygen into a toxic agent that amplifies oxidative stress, disrupts regeneration, and drives pro-growth signals. Restoring bioelectric balance and resistance is a mandatory clinical need and is key to managing the turbocancer state.
CITES
Wang, R.-H., & others (2017). Associations among metabolism, circadian rhythm, and age-associated diseases. Aging and Disease, 8(5), 691–709.
DOI: 10.14336/AD.2016.1101
My Notes: This review by Wang and colleagues discusses the connection between the Warburg effect, tumorigenesis, and circadian rhythms, hypothesizing that circadian disruption activates cell-autonomous transformation to generate the Warburg effect. It emphasizes NAD+-dependent sirtuins (e.g., SIRT1, SIRT3) and clock genes (e.g., CLOCK, BMAL1, PER2) but focuses on genetic and metabolic pathways, potentially overlooking the environmental role of artificial light and light-nitrogen coupling I’ve highlighted. It critically examines this as an establishment narrative that simplifies the Warburg effect as a biochemical adaptation, missing the broader photobiological and quantum context of circadian mismatch from artificial light.
Masri, S., Kinouchi, K., & Sassone-Corsi, P. (2015). The emerging link between cancer, metabolism, and circadian rhythms. Nature Medicine, 21(12), 1795–1803.
DOI: 10.1038/nm.0271-8
My Notes: Masri, Kinouchi, and Sassone-Corsi explore the connection between circadian disruption, cancer metabolism, and the Warburg effect, noting epidemiological links to artificial light at night (e.g., shift work). They discuss clock genes (e.g., CLOCK, BMAL1, CRY, PER) and metabolic reprogramming but focus on transcriptional feedback loops, potentially underestimating the role of light-nitrogen uncoupling, ubiquitin marking, and NAD+/NADH imbalances I’ve emphasized. It challenges the establishment narrative for prioritizing molecular biology over environmental light dynamics, aligning with the interpretation as a circadian mismatch signal.
Sahar, S., & Sassone-Corsi, P. (2009). Metabolism and cancer: The circadian clock connection. Nature Reviews Cancer, 9(12), 886–896.
DOI: 10.1038/nrc2747
My Notes: This review by Sahar and Sassone-Corsi examines how circadian clocks regulate cancer metabolism, including the Warburg effect, and links it to circadian disruption. It mentions light exposure as a zeitgeber but focuses on genetic and biochemical mechanisms (e.g., sirtuins, NAD+), while missing the decentralized photobiological insights about artificial light’s role in uncoupling light-nitrogen cycles and driving ubiquitin and disease. I critically assess this as an establishment perspective that overlooks quantum and surface chemistry roles, supporting my broader model.
Korennykh, A., & others (2019). The metabolites NADP and NADPH are the targets of the circadian protein Nocturnin. Nature Communications, 10(1), 10125.
DOI: 10.1038/s41467-019-10125-z
My Notes: This study by Korennykh and colleagues at Princeton University investigates Nocturnin’s role in fat metabolism and circadian rhythms, showing its action on NADP+/NADPH and NAD+/NADH, linking to energy regulation. It supports my point about NAD+/NADH imbalances in circadian disruption and metabolic diseases (e.g., obesity, diabetes) but focuses on biochemical mechanisms, missing light-nitrogen coupling and ubiquitin dynamics I’ve described. I challenge the establishment narrative for not exploring environmental light’s photobiological impact, aligning with the decentralized reinterpretation of the Warburg effect.
Zhang, Y., Hu, K., Tang, Y., Feng, Q., Jiang, T., Chen, L., Chen, X., Shan, C., Han, C., Chu, W., Ma, N., Hu, H., Gao, H., & Zhang, Q. (2024). Interactive correlations between artificial light at night, health risk behaviors, and cardiovascular health among patients with diabetes: A cross-sectional study. Journal of Diabetes, 16(10), e70008.
DOI: 10.1111/1753-0407.70008
My Notes: This recent study by Zhang et al. links artificial light at night (ALAN) to diabetes, obesity, and cardiovascular health, showing circadian disruption, NAD+ decline, and metabolic changes. It supports the decentralized view of the Warburg effect as a circadian mismatch signal from ALAN. Still, it focuses on behavioral and epidemiological data, missing quantum and photobiological mechanisms (e.g., light-nitrogen, ubiquitin). I critically examine this as an establishment narrative prioritizing classical epidemiology over my decentralized insights.
Engin, A. (2024). Misalignment of circadian rhythms in diet-induced obesity. Advances in Experimental Medicine and Biology, 1460, 27–71.
DOI: 10.1007/978-3-031-63657-8_2
My Notes: Engin’s review connects circadian misalignment (e.g., from artificial light, shift work) to obesity, diabetes, and cancer, including the Warburg effect as a metabolic response. It mentions NAD+, sirtuins, and clock genes but focuses on biochemical and nutritional pathways, potentially overlooking your light-nitrogen coupling and ubiquitin marking. I challenge the centralized establishment narrative for not addressing photobiological and quantum mechanisms, supporting the decentralized reinterpretation as a circadian mismatch driven by artificial light.
GAME, SET, MATCH.
Comments
Dr. Jack Kruse
PAD is caused by blue light and nnEMF. So yes shift work is a great way to get PAD
Deb DeBiase
Dr Kruse, could this also cause hardening of the arteries in someone who ate healthy food but Always worked evenings in the medical profession. Glucose causes inflammation.
Paul Puccini
Random question Dr Jack, which mattress do you sleep on? Can’t seem to find a coil free organic mattress that’s comfortable.
Dr. Jack Kruse
soon you'll find out why this is unwise.
Dr. Jack Kruse
marketing is legalize lying.
Dr. Jack Kruse
Perfectly. MS is the one that has no idea where this goes.
Paul Puccini
What’s your opinion on Orgone Amplifiers?
Robin Fornwalt
How do your observations fit in with the topological conductors just now released by Microsoft? https://www.youtube.com/watch?v=sd86KQfErnA
Dr. Jack Kruse
This new podcast should be an eye-opener for many. A little-known warning from the manufacturer is hidden within your cellphone manual. Do you know what it says? What if I told you it says the NTP study of 11/1/18 is a bigger deal than you want to know? It should be no surprise if you pay attention to the literature that has already documented the health effects of RF and microwave radiation... the inverse square law is your friend. Don’t put this electrosmog by your brain if you want to avoid the healthcare system. Divergent thinking is the center of human creativity, and most people believe we are born with it, but I do not believe this. We can teach people how to think more broadly by learning to examine things we do not believe or accept to see if they have merit or not. Divergent thinking can be acquired and developed as a skill when you get "skin in the game." I now excuse people who sense life with tiny thinking. This brand of expansive thinking is a distinct form of higher-order thinking, and it can be taught to all ages of autodidacts. "Divergents" always give themselves permission to see things differently than crowds. Misunderstanding vanishes when you train yourself to ask, 'What else might the 11/1/18 NTP study on RF radiations imply'? Could it cause neurodegeneration since nnEMF increases AMPk pathways and glucose metabolism? You better start asking better questions, folks. https://www.youtube.com/watch?v=IHSMqhrfvaU
Dicko
I use blue blockers at work and take a red light panel for night shifts. They won’t give us control of the lights, so we can only dim them, but can’t turn them off.
Steven Heckler
Blue Blockers and I think they make clothes that stop or impede nnEMF
Mary B
Does Dr Kruse offer ,by invitation only, an Inner Circle Membership that is not offered on his website?
Mario Luis Garcia
Hello Dr. Kruse, Have you seen this interview with Judy Vary? This is a very detailed account of what you described in the Danny Jones interview. By Shannon Joy on X. Mario Garcia https://x.com/diedsuddenly_/status/1902180337955835961?s=46
Dr. Jack Kruse
WHY ARE EYE DISEASES MORE COMMON TODAY? Check out my latest article: THEY ARE BLINDING US WHILE STOPPING OUR REGENERATION The neurosensory retina is a layered tissue which lines the back of the eye, communicating with the brain via the optic nerve. Blood is supplied to the neurosensory retina by retinal blood vessels originating from the central retinal artery. Transport across retinal blood vessels is limited by endothelial tight junctions, which constitute the inner blood–retinal barrier. Allan Frey's work with DARPA in the 1960s show that nnEMF opens this barrier and makes the eye more susceptible to damage when it is present in our local environment. We forget that the optic nerve is comprised of ganglion cell axons, the “output neurons” of the retina. The retina is built up of three layers of cell bodies and two plexiform layers of synapses, clearly defined on histological sections. The innermost layer is the ganglion cell layer. The inner nuclear layer, featuring the cell bodies of bipolar, amacrine, and horizontal cells, is sandwiched by an internal plexiform layer and ganglion cell layer on one side, and outer plexiform layer and outer nuclear layer on the other. The outer nuclear layer features the cell bodies of most of the photoreceptors: the rods and cones. A third class of photoreceptor, intrinsically photoreceptive ganglion cells (melanopsin blue light detectors), is situated in the ganglion cell layer. All photoreceptors depend on a vitamin A-derived chromophore to detect light and adequate dopamine and melatonin levels to regenerate them in sunlight. The chromophore associated with light transduction proteins, opsins, and undergoes photoisomerization during transduction. Expended melanopsin or neuropsin chromophores then enters the visual cycle, a sequence of reactions which facilitates regeneration and re-association with opsins for further transduction. if regeneration pathways are blocked the free Vitamin become a wrecking ball for the human retina. https://www.linkedin.com/pulse/blinding-us-while-stopping-our-regeneration-jack-kruse-6jsze
Boris Leoro
interesting
Elena Gjorgjieva
this post finally delivers a logical explanation to something i was feeling for a few years before my cancer diagnosis. I started hearing a hum to my body, like an electric appliance.
Dicko
I work in an electrical distribution Control Room on a 24/7 roster. We also had to have the Pfizer jab to keep our jobs. We actually contemplated living at work while the world was going to sh*t to maintain the electrical supply. This blog rings true on so many levels. I need to build a case to change our lights and screens to something that will ease the blue light burden and the studies you mentioned will help. Thank you.
Courtenay Marie
Lynn Miller which brand do you use?
Steven Heckler
BOOM BOOM BOOM BOOM BOOM BOOM
John Gilbertson
CoQ10 made of stars? True, everything is. can it be mitochondriac helpful? researching. a cook.
Divya Darbari
Thank you Uncle Jack, also this blog gave me tremendous insights . Thanks a ton for explaining things so coherently. Even lay people like me could follow the content very properly.
Dr. Jack Kruse
yes it hits all of them
Dr. Jack Kruse
This is nonsense created to create business
Christopher Williams
I have a question about healing of cavitations in someone’s jaw bone….currently surgery seems the most complete as infections are trapped in the bone. What are you thoughts or should I ask on another platform. Thank you.
cL34rC0mm
Susan Spence = https://kruselongevitycenter.com/optimalklubs
Courtenay Marie
Would love your feedback on this video and his work, thank you
Courtenay Marie
https://www.youtube.com/watch?v=z6BprvmZfmQ
michael john moreau
Thank you, Jack, for expounding on the various items you mentioned for those challenged with "Oxygen Allergy". Your aspect of discussion regarding the Warburg Occurrence, shines a brand-new light on the so-called Warburg Effect. I could only understand part of the path with the book called Ravenous, by Sam Apple. I will research further on "said" items, gain some ground, a firm footing, understand Dosey e' Dosey, and apply the three, when my intuitive time ushers in the commencement.
Dr. Jack Kruse
Seyfried is dangerous.
Dr. Jack Kruse
https://x.com/DrJackKruse/status/1900321458468864070
Dr. Jack Kruse
Read what i wrote you on the forum. Answer there.
Divya Darbari
Uncle Jack, I took Pfizer jab before I knew about your work. I have a history of missing periods and I have not gotten my periods for last 11 months. Can the jab have something to do with worsening my symptoms? I am not sure how if my missing cycle is indicative of some sort of major underlying metabolic issue
Jillian
Got cut off...HBOT in general would not help and could possibly hurt is what I'm gathering, yet so many of Seyfried's followers seek out HBOT.
Jillian
The Warburg effect only addresses 7/10 Hallmarks of Cancer. Does this theory hit all 10? I know it's been puzzling to people that there's nothing that does. I saw a comment above about HBOT with
cL34rC0mm
Jesse Gibson = Dr. Jack Kruse has ONLY ONE X account: @DrJackKruse ALL others are impostors, wannabees and FRAUDS! They have no substance so they have to counterfeit the original. If you were an Optimal Klubs - Gold member and follower on the Forum.JackKruse.com you'd know this. https://kruselongevitycenter.com/optimalklubs Keep up-to-date by following Dr. Kruse on social media at facebook or at x.com or Instagram: @DrJackKruse ANYONE else claiming to be Dr. Kruse using a different ID besides @DrJackKruse is NOT Dr. Kruse, but an impostor.
Dr. Jack Kruse
The aftermarket effect of the jab. https://markcrispinmiller.substack.com/p/in-memory-of-those-who-died-suddenly-march-3-10-2025
Susan Spence
How much $ is optimal club… I think I am a bronze member… was it me who asked questions inappropriately on the wrong membership?
John Gilbertson
Tio, just crushed my first Vit D test scored at 50, paid $35. Epi-Paleo at 43d latitude zero D supplements or ice baths. dialing in my U haplo to get cold exposure by simply being outside. BTW Van Wyk is a gift, thank you Tio
Lynn Miller
i still take MB everyday. I learned about it ten years ago from you and never looked back. I have been telling people for 26 years that no one is coming to save us from anything! We are on our own!!
Jesse Gibson
Do you have a 2nd Twitter account or am I getting fucked with. Seemed legit but I just wanted to make sure. Never know with AI now a days.
cL34rC0mm
Susan Spence = ANY and ALL questions directed to Dr. Kruse may be answered in detail ONLY to active OPTIMAL KLUB membership. Especially ANY medical questions. Be aware that Patreon is NOT active membership. To learn much MORE read all of Dr. Kruse's free blogs at: JackKruse.com - as well USE THE SEARCH BOX on the top of each page. Also, signup and join: forum.jackkruse.com Search LinkedIn for Dr. Jack Kruse and read his 200+ free articles/blogs: https://www.linkedin.com/in/drjackkruse/ Search youtube and the internet for all the video/podcast interviews that Dr. Jack Kruse has done. There are 100's! As a paying Patreon here, you pay as little as $5USD per month, you can sample all Dr. Jack Kruse's premium content here at: Patreon.com/DrJackKruse/ IF you want to get even MORE premium content & access monthly (closed to members ONLY) Q & A sessions with Dr. Kruse? It's BEST TO JOIN with =>Gold membership to get the most benefits & most access. And to get your most pressing/personal questions answered by Dr. Kruse, PLUS get more premium content AND get front line access to monthly Q&A CLOSED sessions ONLY for Silver, Gold & Titanium members? https://kruselongevitycenter.com/optimalklubs Keep up-to-date by following Dr. Kruse on social media at facebook or at x.com or Instagram: @DrJackKruse ANYONE else claiming to be Dr. Kruse using a different ID besides @DrJackKruse is NOT Dr. Kruse, but an impostor.
cL34rC0mm
Susan Spence = Freezing RO water does NOTHING for DDW. Your time is better used by drinking DDW already to the ppm you desire. Recommend DrinkLiteWater.com 10ppm. You can mix with your favourite spring water to lessen the deuterium content of the spring water and extend the overall volume of DDW you have available. Lite Water website can show you the proper ratios to mix for best results.
cL34rC0mm
Maia Bulashvilli = ANY and ALL questions directed to Dr. Kruse may be answered in detail ONLY to active OPTIMAL KLUB membership. Especially ANY medical questions. Be aware that Patreon is NOT active membership. To learn much MORE read all of Dr. Kruse's free blogs at: JackKruse.com - as well USE THE SEARCH BOX on the top of each page. Also, signup and join: forum.jackkruse.com Search LinkedIn for Dr. Jack Kruse and read his 200+ free articles/blogs: https://www.linkedin.com/in/drjackkruse/ Search youtube and the internet for all the video/podcast interviews that Dr. Jack Kruse has done. There are 100's! As a paying Patreon here, you pay as little as $5USD per month, you can sample all Dr. Jack Kruse's premium content here at: Patreon.com/DrJackKruse/ IF you want to get even MORE premium content & access monthly (closed to members ONLY) Q & A sessions with Dr. Kruse? It's BEST TO JOIN with =>Gold membership to get the most benefits & most access. And to get your most pressing/personal questions answered by Dr. Kruse, PLUS get more premium content AND get front line access to monthly Q&A CLOSED sessions ONLY for Silver, Gold & Titanium members? https://kruselongevitycenter.com/optimalklubs Keep up-to-date by following Dr. Kruse on social media at facebook or at x.com or Instagram: @DrJackKruse ANYONE else claiming to be Dr. Kruse using a different ID besides @DrJackKruse is NOT Dr. Kruse, but an impostor.
cL34rC0mm
Jeanne Allen = ANY and ALL questions directed to Dr. Kruse may be answered in detail ONLY to active OPTIMAL KLUB membership. Especially ANY medical questions. Be aware that Patreon is NOT active membership. To learn much MORE read all of Dr. Kruse's free blogs at: JackKruse.com - as well USE THE SEARCH BOX on the top of each page. Also, signup and join: forum.jackkruse.com Search LinkedIn for Dr. Jack Kruse and read his 200+ free articles/blogs: https://www.linkedin.com/in/drjackkruse/ Search youtube and the internet for all the video/podcast interviews that Dr. Jack Kruse has done. There are 100's! As a paying Patreon here, you pay as little as $5USD per month, you can sample all Dr. Jack Kruse's premium content here at: Patreon.com/DrJackKruse/ IF you want to get even MORE premium content & access monthly (closed to members ONLY) Q & A sessions with Dr. Kruse? It's BEST TO JOIN with =>Gold membership to get the most benefits & most access. And to get your most pressing/personal questions answered by Dr. Kruse, PLUS get more premium content AND get front line access to monthly Q&A CLOSED sessions ONLY for Silver, Gold & Titanium members? https://kruselongevitycenter.com/optimalklubs Keep up-to-date by following Dr. Kruse on social media at facebook or at x.com or Instagram: @DrJackKruse ANYONE else claiming to be Dr. Kruse using a different ID besides @DrJackKruse is NOT Dr. Kruse, but an impostor.
michael john moreau
Spectacular information, the gift that keeps on giving.
Jeanne Allen
what is the source of methyl-blue.. i read it was from petroleum... great blob btw..
Maia Bulashvili
Thank you for this mind-opening piece!! If I understand your model correctly, restoring mitochondrial membrane potential (Δψ), increasing electrical resistance, and rebuilding mitochondrial water are key to reversing the ‘oxygen allergy’ state. Based on that, what is your opinion on using Intermittent Hypoxia-Hyperoxia Training (IHHT) or hypoxic therapies in general to selectively train mitochondria to tolerate oxygen again and repair Δψ? Wouldn’t IHHT—by cycling hypoxia and controlled hyperoxia—be an ideal tool to reestablish mitochondrial resistance and reduce the pro-oxidative state you describe?
Susan Spence
I’ve been pondering on this since 2006 and now the light is illuminated for me!! I’m sleeping all night and skin is better hydrated… if I freeze RO water and let part of it melt, would that help with DDW? I also have the energy to do more than collapse when I get home! 👍💐
Susan Spence
Now it’s working …i had to tap more than once… thanks for your reply!
Susan Spence
The “see more” tab is not working on your reply Dr. Jack
Dr. Jack Kruse
If your brain has those changes as soon as UVA is present you need to be in it. 30-120 min
Susan Spence
A lot to digest… I can now understand my faulty centralized medicine diagnoses…. I’ve been looking at this stuff from mostly a nutritional deficit… so wrong!!! I’m getting way better!! I have extensive white matter loss due circadian mismatch and blue light exposure…. That doesn’t help with my reasoning!!! I’d rather live… but if given the choice, I’d rather die of my own exploration and trial and error to feel the real changes inside of me… I am a CRNA so I exist under that extra input of blue light, WiFi , and missing sunrise Because I start work at 6:30 AM… I leave early to prepare so I can view the sunrise… what is a reasonable time of adequate exposure to AM early light.
Boris Leoro
Uncle Jack you are so far ahead of the food gurus, Andrew Huberman, and Peter Attia.
Dr. Jack Kruse
Synonyms.
Peter Collins
And everyone thinks DJT & RFKjr are coming to save our asses, the hidden hands are ferociously plotting to complete their dark plans
Ahmet Cem KAYA
“bioelectric dysfunction”
Dr. Jack Kruse
Is what different? Explain yourself.
Ahmet Cem KAYA
Is this different than hypoxia?
Flynn Jones
That’s what I thought. Thanks for clarifying! Guessing it’s not safe whatsoever in this nnEMF world
Dr. Jack Kruse
Did you read and understand the fucking blog? That is a great way to KILL SOMEONE.
Flynn Jones
So interesting! What is your opinion on HBOT with deionised water? If someone has been jabbed is this something to avoid? Been used to treat cancer as its benefits on mitochondria but is it just pushing too much oxygen to someone with an oxygen allergy and having the opposite effect? :)
billy custer
BOOM
Dr. Jack Kruse
This mRNA platform is all about power law math. Not the math most of you think of. MONEY. The Decentralized medical truth is that the closer to the sun, the better off you'll be if you were in the experimental group. That is where the redox power of water can limit the death rate to protect you from a 30-million-volt current running amuck in your body right now. The further away from it and the closer to the technocracy's light you are, the higher your chance of being in the control group. We call that tapering the Ponzi scheme. It is a DARPA scheme for the Treasury. If the same DoD weapon were used in the UK or Toronto, your chance of dying over the next 50 years from a disease would go way up on a relative basis. This is not my opinion; it is based on photo-bioelectric data. It has a lot to do wit electrical resistance in a key spot where that current resides. This is an interesting new blog on the power law math of DARPA epidemics and why MAHA is really HAHA. This article subtracts out the hyperbole and focuses on the math behind the actions of governments. It is not rocket science. It is brain surgery without a scalpel. It is all based on Kleiber's power laws. Your decisions about your environment will determine how fast you obtain your outcome. Solar light and nnEMF choices determine control your redox power. You will not forget Uncle Jack after thinking about what I wrote for the experimental group here. Ponder that for a lifetime now, no matter how long or short it turns out to be. .https://www.patreon.com/posts/decentralized-37-124052365
